OC logo
Libraries Home Start Researching Subject Guides Services About Us
Skip to Main Content

Nursing Research Guide

Guidance for Nurses and Allied Health Researchers

Finding articles

For the best coverage of pathophysiology and physiology, find review articles. In addition to providing you a broad understanding of a condition or disease, you can also use them to find primary, clinical research using citation chaining.

  • Chaining citations backward gives you background and history (systematic reviews will cite each clinical study included) 
    • Use the citations at the end of an article
  • Chaining citations forward give you recent research on your topic    

Topics 2025

Dementia

PubMed keywords- dementia behavior

Watt, J. A., Porter, J., Tavilsup, P., Chowdhury, M., Hatch, S., Ismail, Z., Kumar, S., Kirkham, J., Goodarzi, Z., & Seitz, D. (2024). Guideline Recommendations on Behavioral and Psychological Symptoms of Dementia: A Systematic Review. Journal of the American Medical Directors Association25(5), 837–846.e21. https://doi.org/10.1016/j.jamda.2024.03.007

 

Asthma

PubMed keywords- asthma mechanism

Miller, R. L., Grayson, M. H., & Strothman, K. (2021). Advances in asthma: New understandings of asthma’s natural history, risk factors, underlying mechanisms, and clinical management. Journal of Allergy and Clinical Immunology, 148(6), 1430–1441. https://doi.org/10.1016/j.jaci.2021.10.001

Endometriosis

PubMed keywords- Endometriosis well-being

Sims, O. T., Gupta, J., Missmer, S. A., & Aninye, I. O. (2021). Stigma and Endometriosis: A Brief Overview and Recommendations to Improve Psychosocial Well-Being and Diagnostic Delay. International journal of environmental research and public health18(15), 8210. https://doi.org/10.3390/ijerph18158210

 

CHF

PubMed Keywords- chronic heart failure compliance

Ding, H., Jayasena, R., Chen, S. H., Maiorana, A., Dowling, A., Layland, J., Good, N., Karunanithi, M., & Edwards, I. (2020). The Effects of Telemonitoring on Patient Compliance With Self-Management Recommendations and Outcomes of the Innovative Telemonitoring Enhanced Care Program for Chronic Heart Failure: Randomized Controlled Trial. Journal of medical Internet research22(7), e17559. https://doi.org/10.2196/17559

Acute respiratory failure and hypoxia

PubMed keywords- Acute respiratory failure hypoxia physiology

Grieco, D. L., Maggiore, S. M., Roca, O., Spinelli, E., Patel, B. K., Thille, A. W., Barbas, C. S. V., de Acilu, M. G., Cutuli, S. L., Bongiovanni, F., Amato, M., Frat, J. P., Mauri, T., Kress, J. P., Mancebo, J., & Antonelli, M. (2021). Non-invasive ventilatory support and high-flow nasal oxygen as first-line treatment of acute hypoxemic respiratory failure and ARDS. Intensive care medicine47(8), 851–866. https://doi.org/10.1007/s00134-021-06459-2

PTSD and coronary artery disease

PubMed Keywords- PTSD CAD mechanism

Sumner, J. A., Cleveland, S., Chen, T., & Gradus, J. L. (2023). Psychological and biological mechanisms linking trauma with cardiovascular disease risk. Translational psychiatry13(1), 25. https://doi.org/10.1038/s41398-023-02330-8

COPD

PubMed keywords- COPD pathophysiology

Gomes, F., & Cheng, S. L. (2023). Pathophysiology, Therapeutic Targets, and Future Therapeutic Alternatives in COPD: Focus on the Importance of the Cholinergic System. Biomolecules13(3), 476. https://doi.org/10.3390/biom13030476

 

Preeclampsia

Ives, C. W., Sinkey, R., Rajapreyar, I., Tita, A. T. N., & Oparil, S. (2020). Preeclampsia-Pathophysiology and Clinical Presentations: JACC State-of-the-Art Review. Journal of the American College of Cardiology76(14), 1690–1702. https://doi.org/10.1016/j.jacc.2020.08.014

 

Pancreatitis

De Lucia, S. S., Candelli, M., Polito, G., Maresca, R., Mezza, T., Schepis, T., Pellegrino, A., Zileri Dal Verme, L., Nicoletti, A., Franceschi, F., Gasbarrini, A., & Nista, E. C. (2023). Nutrition in Acute Pancreatitis: From the Old Paradigm to the New Evidence. Nutrients15(8), 1939. https://doi.org/10.3390/nu15081939

 

Type 2 DM

 

Minari, T. P., Tácito, L. H. B., Yugar, L. B. T., Ferreira-Melo, S. E., Manzano, C. F., Pires, A. C., Moreno, H., Vilela-Martin, J. F., Cosenso-Martin, L. N., & Yugar-Toledo, J. C. (2023). Nutritional Strategies for the Management of Type 2 Diabetes Mellitus: A Narrative Review. Nutrients15(24), 5096. https://doi.org/10.3390/nu15245096

 

Necrotizing Fasciitis

Suijker, J., Stoop, M., Meij-de Vries, A., Pijpe, A., Boekelaar, A., Egberts, M., & Van Loey, N. (2023). The impact of necrotizing soft tissue infections on the lives of survivors: a qualitative study. Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation32(7), 2013–2024. https://doi.org/10.1007/s11136-023-03371-8

 

hepatocellular cholangiocarcinoma

Krishna M. (2021). Pathology of Cholangiocarcinoma and Combined Hepatocellular-Cholangiocarcinoma. Clinical liver disease17(4), 255–260. https://doi.org/10.1002/cld.1047

 

Systemic Lupus

Charras, A., Smith, E., & Hedrich, C. M. (2021). Systemic Lupus Erythematosus in Children and Young People. Current rheumatology reports23(3), 20. https://doi.org/10.1007/s11926-021-00985-0

 

Hypovolemic Shock and acute kidney injury

Kashani, K., Omer, T., & Shaw, A. D. (2022). The Intensivist's Perspective of Shock, Volume Management, and Hemodynamic Monitoring. Clinical journal of the American Society of Nephrology : CJASN17(5), 706–716. https://doi.org/10.2215/CJN.14191021

 

Schizophrenia

Riehle, M., Straková, A., & Lincoln, T. M. (2024). Emotional Experience of People With Schizophrenia and People at Risk for Psychosis: A Meta-Analysis. JAMA psychiatry81(1), 57–66. https://doi.org/10.1001/jamapsychiatry.2023.3589

 

Hypertension

Kassavou, A., Wang, M., Mirzaei, V., Shpendi, S., & Hasan, R. (2022). The Association Between Smartphone App-Based Self-monitoring of Hypertension-Related Behaviors and Reductions in High Blood Pressure: Systematic Review and Meta-analysis. JMIR mHealth and uHealth10(7), e34767. https://doi.org/10.2196/34767

 

Parkinson's disease

van der Berg, I., Schootemeijer, S., Overbeek, K., Bloem, B. R., & de Vries, N. M. (2024). Dietary Interventions in Parkinson's Disease. Journal of Parkinson's disease14(1), 1–16. https://doi.org/10.3233/JPD-230366

 

Graves' disease

Kahaly G. J. (2020). Management of Graves Thyroidal and Extrathyroidal Disease: An Update. The Journal of clinical endocrinology and metabolism105(12), 3704–3720. https://doi.org/10.1210/clinem/dgaa646

 

Infective endocarditis

Mills, M. T., Al-Mohammad, A., & Warriner, D. R. (2022). Changes and advances in the field of infective endocarditis. British journal of hospital medicine (London, England : 2005)83(3), 1–11. https://doi.org/10.12968/hmed.2021.0510

 

Lung cancer

Takemura, N., Cheung, D. S. T., Fong, D. Y. T., Lee, A. W. M., Lam, T. C., Ho, J. C., Kam, T. Y., Chik, J. Y. K., & Lin, C. C. (2024). Effectiveness of Aerobic Exercise and Tai Chi Interventions on Sleep Quality in Patients With Advanced Lung Cancer: A Randomized Clinical Trial. JAMA oncology10(2), 176–184. https://doi.org/10.1001/jamaoncol.2023.5248

 

Peripheral artery disease

Narula, N., Olin, J. W., & Narula, N. (2020). Pathologic Disparities Between Peripheral Artery Disease and Coronary Artery Disease. Arteriosclerosis, thrombosis, and vascular biology40(9), 1982–1989. https://doi.org/10.1161/ATVBAHA.119.312864

 

Supraventricular tachycardia

Ahmad, F., Abu Sneineh, M., Patel, R. S., Rohit Reddy, S., Llukmani, A., Hashim, A., Haddad, D. R., & Gordon, D. K. (2021). In The Line of Treatment: A Systematic Review of Paroxysmal Supraventricular Tachycardia. Cureus13(6), e15502. https://doi.org/10.7759/cureus.15502

Example Topics and Techniques 2023

Systemic Lupus- Review article

Found in PubMed, Keywords- systemic lupus pathophysiology

Fanouriakis, A., Tziolos, N., Bertsias, G., & Boumpas, D. T. (2021). Update οn the diagnosis and management of systemic lupus erythematosus. Annals of the Rheumatic Diseases80(1), 14–25. https://doi.org/10.1136/annrheumdis-2020-218272

 

Hypertension- Review article

Found in PubMed, Keywords- Hypertension physiology

Richards, E. M., Li, J., Stevens, B. R., Pepine, C. J., & Raizada, M. K. (2022). Gut Microbiome and Neuroinflammation in Hypertension. Circulation Research130(3), 401–417. https://doi.org/10.1161/CIRCRESAHA.121.319816

 

Opioid & alcohol misuse- Primary research

Found in CINAHL, Keywords opioid and alcohol use disorder 

Sübay, , Büşra, & Sönmez, M. B. (2021). Interoceptive Awareness, Decision-Making and Impulsiveness in Male Patients with Alcohol or Opioid Use Disorder. Substance Use & Misuse56(9), 1275–1283. https://doi.org/10.1080/10826084.2021.1914108

 

Breast cancer- Primary research

Found in CINAHL, Keywords Breast cancer AND lived experience

Potter, A. M., Bentz, B., Crue, L., Leiby, S., Bashi, S., Maguire, K., Meyers, J., & Mieczkowski, K. (2023). Men’s Lived Experiences of Breast Cancer and Changes in Occupation. Occupational Therapy International, 1–10. https://doi.org/10.1155/2023/9641922

 

Ischemic stroke- Review article

Found in PubMed, Keyword Ischemic stroke behavior

Pluta, R., Januszewski, S., & Czuczwar, S. J. (2021). The Role of Gut Microbiota in an Ischemic Stroke. International journal of molecular sciences22(2), 915. https://doi.org/10.3390/ijms22020915

 

Celiac disease- Primary research

Found in CINAHL, Keywords- Celiac disease AND experien*

Dalton, J., & Castellanos, D. C. (2023). The Exploration of the Eating Experience in Adults with Celiac Disease: A Phenomenological Qualitative Study. Journal of the Academy of Nutrition & Dietetics123(4), 593–601.https://doi.org/10.1016/j.jand.2022.08.130

 

Myocardial infarction- Review article

Found in PubMed, Keywords- myocardial infarction

Saleh, M., & Ambrose, J. A. (2018). Understanding myocardial infarction. F1000Research7, F1000 Faculty Rev-1378. https://doi.org/10.12688/f1000research.15096.1

 

COPD- Primary research

Found in CINAHL, Keywords- COPD AND stress

Cekic, Y., Bulut, T. Y., & Avci, İ. A. (2022). The Effect of Provision of Information and Supportive Nursing Care on Blood Gas, Vital Signs, Anxiety, Stress, and Agitation Levels in COPD Patients Treated with NIV: A Randomized Controlled Trial. Indian Journal of Critical Care Medicine26(9), 1011–1018. https://doi.org/10.5005/jp-journals-10071-24315

 

Irritable bowel- Primary research

Found in CINAHL, Keywords- Irritable bowel AND experien*

Frändemark, Å., Törnblom, H., Simrén, M., & Jakobsson, S. (2022). Maintaining work life under threat of symptoms: a grounded theory study of work life experiences in persons with Irritable Bowel Syndrome. BMC Gastroenterology22(1), 1–9. https://doi.org/10.1186/s12876-022-02158-4

 

Type 2 Diabetes- Review

Owens-Gary, M. D., Zhang, X., Jawanda, S., Bullard, K. M., Allweiss, P., & Smith, B. D. (2019). The Importance of Addressing Depression and Diabetes Distress in Adults with Type 2 Diabetes. Journal of general internal medicine34(2), 320–324. https://doi.org/10.1007/s11606-018-4705-2

 

Hypertriglyceridemia-induced pancreatitis- Review

Found with citation chaining in Google Scholar

Yang, A. L., & McNabb-Baltar, J. (2020). Hypertriglyceridemia and acute pancreatitis. Pancreatology20(5), 795-800. https://doi.org/10.1016/j.pan.2020.06.005

 

Scleroderma- Primary research

Found via CINAHL & Google Scholar- Keywords scleroderma AND experien*

Flurey, C. A., Pauling, J. D., Saketkoo, L. A., Denton, C. P., Galdas, P., Khanna, D., Williams, A., & Hughes, M. (2023). “I turned in my man card”: a qualitative study of the experiences, coping styles and support needs of men with systemic sclerosis. Rheumatology62(6), 2160–2167.

 

Alzheimer's disease- Primary research

Yu, F., Vock, D. M., Zhang, L., Salisbury, D., Nelson, N. W., Chow, L. S., Smith, G., Barclay, T. R., Dysken, M., & Wyman, J. F. (2021). Cognitive Effects of Aerobic Exercise in Alzheimer's Disease: A Pilot Randomized Controlled Trial. Journal of Alzheimer's disease : JAD80(1), 233–244. https://doi.org/10.3233/JAD-201100

Assignment Details

On your topic of interest you will need articles regarding human response to illness, touching on these 4 elements:

· Physiologic

· Pathophysiologic

· Experiential

· Behavioral

Here is an example paper that discusses each aspect of this framework—

To search effectively for your sources you MUST develop your background knowledge. Read a couple background articles to guide keyword selection. If your searches are not working well, back up, and improve your searches by improving your keywords.

 

Few topics will support searching  "human response to illness" or "behavior" along with the condition you are researching, they are the exception. Mostly, you will need to understand the framework and find the elements of the framework as you do your background reading. Once you determine which specific element you want to explore— your sources will be easier to find.

Keyword and Article Examples 2024

1. Constipation following a surgical procedure

KEYWORDS-

postoperative ileus or postoperative constipation,

Constipation--Prevention and Control,

Surgical OR postoperative Patients

Found in CINAHL

Trads, M., Deutch, S. R., & Pedersen, P. U. (2018). Supporting patients in reducing postoperative constipation: fundamental nursing care–A quasi‐experimental study. Scandinavian Journal of Caring Sciences32(2), 824-832.  https://doi.org/10.1111/scs.12513

2. Diabetes and genetic predisposition

KEYWORDS- 

Diabetes AND genetics

Diabetes AND epigenetics (This article is an excellent overview of the topic of epigenetics in regards to Diabetes and obesity)

This is still pretty broad, so I added "social"

Found in CINAHL

Nosrati, E., Jenum, A. K., Tran, A. T., Marmot, S. M., & King, L. P. (2018). Ethnicity and place: the geography of diabetes inequalities under a strong welfare state. European Journal of Public Health28(1), 30–34. https://doi.org/10.1093/eurpub/ckx119

3. Multiple Sclerosis

KEYWORDS-

Multiple Sclerosis AND human response

Found in CINAHL

Encarnacao, P., Costa Oliveira, C., & Martins, T. (2018). Suffering, a Concept Present in Non-Cancer Patients: Multiple Sclerosis Patients. International Journal of Caring Sciences, 572–578.

4. Ulcerative colitis

KEYWORDS-

Ulcerative colitis AND quality of life

Found in CINAHL

Armuzzi, A., Tarallo, M., Lucas, J., Bluff, D., Hoskin, B., Bargo, D., Cappelleri, J. C., Salese, L., & daCosta DiBonaventura, M. (2020). The association between disease activity and patient-reported outcomes in patients with moderate-to-severe ulcerative colitis in the United States and Europe. BMC Gastroenterology20(1), 1–11. https://doi.org/10.1186/s12876-020-1164-0

5. Diabetes Mellitus in Mexican-American 

KEYWORDS-

Diabetes AND Latino

Found in CINAHL

Morales, J., Glantz, N., Larez, A., Bevier, W., Conneely, M., Fan, L., Reed, B., Alatorre, C., Paczkowski, R., Ahmed, T., Mackenzie, A., Duncan, I., & Kerr, D. (2020). Understanding the impact of five major determinants of health (genetics, biology, behavior, psychology, society/environment) on type 2 diabetes in U.S. Hispanic/Latino families: Mil Familias - a cohort study. BMC Endocrine Disorders, 20(1), 1–13. https://doi/.org/10.1186/s12902-019-0483-z

6. Chronic pain  pathophysiology 

KEYWORDS- searched as stated above in PubMed

Malfliet, A., Kregel, J., Coppieters, I., De Pauw, R., Meeus, M., Roussel, N., Cagnie, B., Danneels, L., & Nijs, J. (2018). Effect of pain neuroscience education combined with cognition-targeted motor control training on chronic spinal pain: a randomized clinical trial. JAMA neurology75(7), 808-817. doi:10.1001/jamaneurol.2018.0492

7. Guillan-Barre and COVID-19

KEYWORDS- searched as above, in PubMed

Khan, F., Sharma, P., Pandey, S., Sharma, D., V, V., Kumar, N., Shukla, S., Dandu, H., Jain, A., Garg, R. K., & Malhotra, H. S. (2021). COVID-19-associated Guillain-Barre syndrome: Postinfectious alone or neuroinvasive too? Journal of Medical Virology93(10), 6045–6049. https://doi.org/10.1002/jmv.27159

8. Coronary artery disease recovery AND depression

KEYWORDS- searched as above, found in CINAHL

da Cunha, D. M. M., dos Anjos, T. S., Lisboa Gois, C. F., de Mattos, M. C. T., Carvalho, L. V., de Carvalho, J., Silva, F. A., Silveira Sobral, D. A., de Mendonça Fialho, K., & Llapa Rodriguez, E. O. (2016). Depressive symptoms in patients with coronary artery disease. Investigacion & Educacion En Enfermeria34(2), 323–328. https://doi.org/10.17533/udea.iee.v34n2a12

9. Pediatric type 2 Diabetes or pre-diabetes

KEYWORDS- 

Pediatric type 2 diabetes AND human response

Found in CINAHL

Skoranski, A., Kelly, N. R., Radin, R. M., Thompson, K. A., Galescu, O., Demidowich, A. P., Brady, S. M., Chen, K. Y., Tanofsky-Kraff, M., Yanovski, J. A., & Shomaker, L. B. (2018). Relationship of Mindfulness to Distress and Cortisol Response in Adolescent Girls At-Risk for Type 2 Diabetes. Journal of Child & Family Studies27(7), 2254–2264. https://doi.org/10.1007/s10826-018-1065-9

10. Idiopathic pulmonary fibrosis 

KEYWORDS-

idiopathic pulmonary fibrosis AND mood

Found in CINAHL

Janssen, K., Rosielle, D., Wang, Q., & Kim, H. J. (2020). The impact of palliative care on quality of life, anxiety, and depression in idiopathic pulmonary fibrosis: a randomized controlled pilot study. Respiratory Research21(1), 1–9. https://doi.org/10.1186/s12931-019-1266-9